Exhaled breath analysis offers a painless window into airway inflammation, yet its clinical adoption is limited by a shortage of robust biomarkers. Hydrogen sulfide (H2S) has been detected in biological fluids, but its diagnostic value across asthma severities is not well established. In this study, we integrated an electrochemical H2S sensor with a detection limit of 1 ppb into the MISTRAL platform. We evaluated exhaled H2S in a prospective cohort of 28 adult asthmatic patients. Mean exhaled H2S concentrations were…